WASHINGTON – On April 6, the U.S. Drug Enforcement Administration sent a letter to federal, state, and local law enforcement partners warning of a nationwide spike in fentanyl-related mass-overdose events.  Administrator Anne Milgram outlined the current threat and offered DEA support to law enforcement officers responding to overdose incidents.

“Fentanyl is killing Americans at an unprecedented rate,” said DEA Administrator Anne Milgram, in a news release. “Already this year, numerous mass-overdose events have resulted in dozens of overdoses and deaths. Drug traffickers are driving addiction, and increasing their profits, by mixing fentanyl with other illicit drugs. Tragically, many overdose victims have no idea they are ingesting deadly fentanyl, until it’s too late.”

Fentanyl-related mass-overdose events, characterized as three or more overdoses occurring close in time and at the same location, have happened in at least seven American cities in recent months, resulting in 58 overdoses and 29 deaths. Cities impacted include Wilton Manors, Florida; Austin, Texas; Cortez, Colorado; Commerce City, Colorado; Omaha, Nebraska; St. Louis, Missouri; and Washington, D.C.

Events like these are being driven by fentanyl, the DEA release said.

Fentanyl is highly-addictive, found in all 50 states, and drug traffickers are increasingly mixing it with other illicit drugs—in powder and pill form—in an effort to drive addiction and attract repeat buyers.

These mass-overdose events typically occur in one of the following recurring scenarios, the DEA said.

1) When drug dealers sell their product as “cocaine,” when it actually contains fentanyl;

2) or when drug dealers sell pills designed to appear nearly identical to legitimate prescriptions, but are actually fake prescription pills containing fentanyl.

This is creating a frightening nationwide trend where many overdose victims are dying after unknowingly ingesting fentanyl, the release said.

The CDC estimated that in the 12-month period ending in October 2021, more than 105,000 Americans died of drug overdoses, with 66 percent of those deaths related to synthetic opioids like fentanyl.

Last year, the United States suffered more fentanyl-related deaths than gun- and auto-related deaths combined.

When a mass-overdose event occurs, DEA said it will assist law enforcement partners, including:

Interdicting the substance that is driving the spike in overdoses;
Investigating and identifying the dealers and larger drug trafficking organizations responsible for the overdose event;
Providing priority access to all of DEA’s resources, including its labs, chemists, and overdose subject matter experts;
Assisting with the presentation of the investigation to federal prosecutors; and
Warning the public about the lethal drug threat.

"Fentanyl poisonings are at an all-time high,” said Sheriff Mike Milstead, Minnehaha County, South Dakota Chair, Drug Enforcement Committee, National Sheriffs' Association. “These are not isolated incidents. These are happening in every state and every county in America, leaving behind grieving families. Let us be clear: These poisonings are part of a strategic maneuver by the cartels and it must be stopped. The nation's Sheriffs appreciate the spotlight that the Drug Enforcement Administration has put on this horrifying spike of fentanyl poisonings and is committed to putting an end to this tragic trajectory.”

DEA is working to trace mass-overdose events back to the local drug trafficking organizations and international cartels responsible for the surging domestic supply of fentanyl.

 In the first three months of 2022, DEA has seized almost 2,000 pounds of fentanyl and one million fake pills. Last year, DEA seized more than 15,000 pounds of fentanyl—four times the amount seized in 2017—which is enough to kill every American.

Today’s warning expands on DEA’s September 2021 Public Safety Alert on the increase in the availability and accessibility of fake prescription pills containing fentanyl.

For more information on the threat of fentanyl and other synthetic opioids, visit DEA.gov.